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UK-NOTPR-1010 | April 2022

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Pipeline

Therapies in development

Our research and development teams aim to target the underlying mechanisms of brain disease. We move together towards a singular goal to deliver therapies that redefine the standard of care for patients and address the areas in brain disease where we see the greatest unmet need.

Project Area Phase 1 Phase 2 Phase 3 Filing
Lu AF28996 (D1-D2 agonist)⁷ Neurology 1
Lu AF82422 (anti-alpha-synuclein mAb) Neurology 2
Lu-AF41156 (D2 agonist) Psychiatry Filing
Lu AG13909 (anti-ACTH mAb)⁴ Neurology 1
Lu AG06466 (MAGL inhibitor) Psychiatry + Neurology 1
Lu AG22515 (CD40L blocker)⁹ Neurology 1
Lu AG09222 (anti-PACAP mAb)³ Neurology 2

Project Area Phase 1 Phase 2 Phase 3 Filing
Lu AF28996 (D1-D2 agonist)⁷ Neurology 1
Lu AF82422 (anti-alpha-synuclein mAb) Neurology 2
Lu-AF41156 (D2 agonist) Psychiatry Filing
Lu AG13909 (anti-ACTH mAb)⁴ Neurology 1
Lu AG06466 (MAGL inhibitor) Psychiatry + Neurology 1
Lu AG22515 (CD40L blocker)⁹ Neurology 1
Lu AG09222 (anti-PACAP mAb)³ Neurology 2

* CD40L/serum-albumin bispecific antibody-fragment ((scFv)2-Fab)) based on AprilBio’s SAFA™ technology platform.

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